| 1. The following are characteristic of Alcohol Dependency Syndrome as described by Edwards: | |
| A. Tolerance |
T
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| B. Withdrawal symptoms |
T
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| C. Narrowing of repetoire |
T
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| D. Desire for need to help |
F
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| E. Salience of drinking |
T
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| 2. Regarding the epidemiology of alcohol dependence: | |
| A. Equal sex prevalence |
F
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| B. Women tend to present later |
T
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| C. Women are more likely to develop physical complications |
T
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| D. Higher rates in the divorced or separated |
T
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| E. Lower rates in ‘middle’ social groups |
T
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| 3. The following are true: | |
| A. Higher rates of alcoholism among 1st degree relatives of alcoholics |
T
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| B. Higher rates of childhood conduct disorder |
T
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| C. Adopted sons of alcoholics have no greater risk of developing the disorder |
F
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| D. Associations with the D2 receptor |
T
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| E. Association with antisocial personality disorder |
T
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| 4. The following biochemical effects of alcohol are recognized: | |
| A. Dopamine release in the nucleus basalis |
F
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| B. 5-HT antagonism |
F
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| C. Potentiation of NMDA receptor channels in glutamate receptor |
F
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| D. Inhibition of GABA receptor complex |
F
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| E. Craving may be due to Dopamine release |
T
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| 5. The following are complications of alcohol misuse: | |
| A. Gastric carcinoma |
T
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| B. Colorectal carcinoma |
T
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| C. Diabetes mellitus |
T
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| D. Renal agenesis |
F
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| E. Zieve’s syndrome |
T
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| 6. The following are recognized neurological complications of alcohol misuse: | |
| A. Central pontine myelinolysis |
T
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| B. Auditory hallucinations in clear consciousness |
T
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| C. Extra-campine hallucinations |
F
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| D. Optic atrophy |
T
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| E. Peripheral neuropathy |
T
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| 7. The following are features of the Foetal Alcohol Syndrome: | |
| A. Normal IQ |
F
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| B. Renal abnormalities |
T
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| C. Cleft palate |
T
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| D. Congenital heart disease |
T
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| E. Macrocephaly |
F
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| 8. The following are recognized psychiatric complications of alcohol misuse: | |
| A. Major depressive illness |
T
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| B. Suicide |
T
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| C. Schizophrenia |
T
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| D. Morbid jealousy |
T
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| E. Dementia |
T
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| 9. The following are characteristic of Wernicke’s encephalopathy: | |
| A. Clouding of consciousness |
T
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| B. Visual hallucinations |
F
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| C. Ataxia |
T
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| D. Ophthalmoplegia |
T
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| E. Hypertension |
F
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| 10. Features of Korsakoff’s psychosis may include: | |
| A. Amnesia |
T
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| B. Higher prevalence in women | F |
| C. Orientation | F |
| D. Confabulation |
T
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| E. Later onset in women |
F
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| 11. Structures affected by Korsakoff’s syndrome typically include: | |
| A. Nucleus accumbens |
F
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| B. Mamillary bodies |
T
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| C. Floor of the third ventricle |
F
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| D. Thalamic nuclei |
T
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| E. Frontal lobes |
T
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| 12. Features of alcoholic pellagra encephalopathy may include: | |
| A. Due to niacin deficiency |
T
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| B. Seizures |
F
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| C. Confusion |
T
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| D. Hypersomnia |
F
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| E. Clasp-knife rigidity |
F
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| 13. Regarding the epidemiology of drug misuse: | |
| A. More common in men |
T
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| B. Most cases begin after the age of 18 |
F
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| C. Most people present after 6-12 months of continuous use |
F
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| D. Around 15 % of opiate addicts have attempted suicide |
T
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| E. 75 % of addicts meet criteria for another psychiatric diagnosis |
T
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| 14. The following have been suggested in the aetiology of drug misuse: | |
| A. Abnormalities of 5-HT systems |
T
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| B. Secondary reinforcement |
T
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| C. ‘Peer group activation’ |
T
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| D. Projection |
F
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| E. Reaction formation |
F
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| 15. The following statements are true: | |
| A. Cocaine acts on the 5-HT system |
F
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| B. Hallucinogens increase dopamine activity |
F
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| C. PCP acts on the gluatamate receptor |
T
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| D. Ecstasy is a 5-HT agonist |
F
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| E. Cannabinoids bind to the GABA receptor |
F
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| 16. Features suggestive of a poor outcome in drug misuse may include: | |
| A. Episodic use |
F
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| B. Antisocial personality disorder |
T
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| C. Late onset of abuse |
F
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| D. Short history of use |
F
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| E. Early drop-out from maintenance programs |
T
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